affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Texas at Houston - Department of Radiation Oncology, affiliation not provided to SSRN, affiliation not provided to SSRN, University of South Alabama, Memorial Sloan Kettering Cancer Center, Rush University - Rush University Medical Center, Harvard University - Beth Israel Deaconess Medical Center, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pittsburgh, University of Alabama at Birmingham, Yeshiva University - Montefiore Medical Center, University of Minnesota - Minneapolis and University of Alabama at Birmingham