University of Pittsburgh, University of Pittsburgh - School of Medicine, University of Pittsburgh - School of Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pittsburgh - School of Medicine, University of Pittsburgh - School of Medicine, University of Pittsburgh - School of Medicine, Virginia Mason Franciscan Health, University of Pittsburgh - School of Medicine, West Virginia University, affiliation not provided to SSRN, - School of Medicine, Government of the United States of America - VA Pittsburgh Healthcare System, affiliation not provided to SSRN, University of Pittsburgh - School of Medicine, University of Pittsburgh and University of Pittsburgh