Luis Carlos Sarmiento Angulo Cancer Treatment and Research Center (CTIC), Instituto Nacional de Cancerología México, Universidad de los Andes, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Luis Carlos Sarmiento Angulo Cancer Treatment and Research Center (CTIC), University of Maryland, College Park, Centro Oncológico Aliada, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United States of America - Miami VA Healthcare System, University of Toronto - University Health Network and Centro de Investigaciones y Manejo del Cáncer