Fudan University, Fudan University, Fudan University, Fudan University, Fudan University, Fudan University, Fudan University, Fudan University, Fudan University - Shanghai Public Health Clinical Center, Fudan University - Shanghai Public Health Clinical Center, Fudan University, Fudan University - Shanghai Public Health Clinical Center, Fudan University, Fudan University, Fudan University - State Key Laboratory of Genetic Engineering, Stemirna Therapeutics Co., Ltd., Stemirna Therapeutics Co., Ltd., Stemirna Therapeutics Co., Ltd., Stemirna Therapeutics Co., Ltd., affiliation not provided to SSRN, Fudan University, Tongji University, Fudan University - Shanghai Public Health Clinical Center, University of Toronto and Fudan University