affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Ghana Medical School, Korle Bu Teaching Hospital, University of Ghana Medical School, University of Rochester - School of Medicine and Dentistry, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Ghana Medical School, Korle Bu Teaching Hospital, affiliation not provided to SSRN, University of Cincinnati and University of Florida - Emerging Pathogens Institute