Shangwei Huangfu

ShanghaiTech University

393 Middle Huaxia Road, Pudong

Shanghai, 201210

China

  • ShanghaiTech University

SCHOLARLY PAPERS

3

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89

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0

Scholarly Papers (3)

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1.

Fine-Tuning Phenoxy Silyl Scaffolds for the Development of Glutathione-Responsive Prodrugs and Antibody−Drug Conjugates

Downloads 40 (953,759)

Fine-Tuning Phenoxy Silyl Scaffolds for the Development of Glutathione-Responsive Prodrugs and Antibody−Drug Conjugates

Number of pages: 16 Posted: 30 Aug 2024
Hongli Chen, Ding Wei, Huihui Wang, Shangwei Huangfu, Yuecheng Jiang, Xianqiang Yu and Biao Jiang
ShanghaiTech University - Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University and ShanghaiTech University
Downloads 20 (1,215,761)

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phenoxy silyl scaffold, antibody-drug conjugate, prodrug, GSH-cleavage

Fine-Tuning Phenoxy Silyl Scaffolds for the Development of Glutathione-Responsive Prodrugs and Antibody−Drug Conjugates

Number of pages: 17 Posted: 19 Dec 2024
Hongli Chen, Ding Wei, Huihui Wang, Shangwei Huangfu, Qi Cheng, Yuecheng Jiang, Xianqiang Yu and Biao Jiang
ShanghaiTech University - Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University and ShanghaiTech University
Downloads 13 (1,307,304)

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phenoxy silyl scaffold, antibody-drug conjugate, Prodrug, GSH-cleavage

Fine-Tuning Phenoxy Silyl Scaffolds for the Development of Glutathione-Responsive Prodrugs and Antibody−Drug Conjugates

Number of pages: 16 Posted: 08 Oct 2024
Hongli Chen, Ding Wei, Huihui Wang, Shangwei Huangfu, Yuecheng Jiang, Xianqiang Yu and Biao Jiang
ShanghaiTech University - Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University and ShanghaiTech University
Downloads 7 (1,370,194)

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phenoxy silyl scaffold, antibody-drug conjugate, prodrug, GSH-cleavage

2.

Triptolide-Based Cleavable Antibody-Drug Conjugates for Pancreatic Cancer

Number of pages: 48 Posted: 04 Apr 2025
Hongli Chen, Huihui Wang, Shangwei Huangfu, Ding Wei, Ziyu Sun, Yifan Wu, Xianqiang Yu and Biao Jiang
ShanghaiTech University - Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University and ShanghaiTech University
Downloads 35 (1,004,043)

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Triptolide, Pancreatic cancer, silyl ether, Antibody-drug conjugates

3.

Deuterium Substitution at the Intolerable Site as a Strategy to Mitigate the Toxicity of Camptothecin Derivatives

Number of pages: 23 Posted: 18 Apr 2025
Hongli Chen, Xianqiang Yu, Ziyu Sun, Jing Liu, Shangwei Huangfu, Qi Cheng, Jiakang Chen and Biao Jiang
ShanghaiTech University - Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University, ShanghaiTech University and ShanghaiTech University
Downloads 14 (1,249,763)

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Camptothecin, Deuterium substitution, Toxicity, In vivo efficacy