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Jessica M. Michael

Saint Louis University

220 North Grand Boulevard

St. Louis, MO 63103

United States

  • Saint Louis University

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Scholarly Papers (1)

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Advancing Mitochondrial Therapeutics: Synthesis and Pharmacological Evaluation of Pyrazole-Based Inhibitors Targeting the Mitochondrial Pyruvate Carrier

Number of pages: 56 Posted: 04 Sep 2024
Lingaiah Maram, Jessica M. Michael, Henry Politte, Vaishnavi S. Srirama, Aymen Hadji, Mohammad Habibi, Meredith O. Kelly, Brian Finck, Lamees Hegazy, Kyle S. McCommis and BAHAA ELGENDY
Washinton University In Saint Louis, School of Medicine, Saint Louis University, Washington University School of Medicine, Saint Louis University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Washington University in St. Louis - Center for Human Nutrition, affiliation not provided to SSRN, Washington University in St. Louis - Center for Human Nutrition and Washington University in St. Louis School of Medicine
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Abstract:

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Mitochondrial Pyruvate Carrier (MPC), Pyrazole-Based Inhibitors, Mitochondrial Therapeutics, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Structure-Activity Relationship (SAR), Mitochondrial Pyruvate Metabolism