affiliation not provided to SSRN, affiliation not provided to SSRN, École Polytechnique Fédérale de Lausanne (EPFL) - Biomolecular Screening Facility, affiliation not provided to SSRN, Universidad de los Andes, Colombia, Uppsala University, Children’s Research Center, University Children’s Hospital of Zurich, University of Zurich, University of Zurich - Institute of Molecular Life Sciences, Uppsala University and affiliation not provided to SSRN