Guy’s and St Thomas’ NHS Foundation Trust - FRCR, Department of Clinical Haematology and Oncology, Mid and South Essex University Hospitals Group, University of British Columbia (UBC), St George's University Hospitals NHS Foundation Trust, University of Texas at Houston - MD Anderson Cancer Center, Velindre University NHS Trust, University College London - Department of Oncology, Institute of Cancer Research (ICR) - Clinical Trials and Statistics Unit (ICR-CTSU), NHS Foundation Trust - Royal Marsden Hospital, Institute of Cancer Research (ICR), H. Lee Moffitt Cancer Center and Research Institute, University of Texas at Houston - MD Anderson Cancer Center, Velindre University NHS Trust, Velindre University NHS Trust, Institute of Cancer Research (ICR), East and North Hertfordshire NHS Trust, NHS Foundation Trust - Addenbrooke's Hospital and Royal Marsden NHS Foundation Trust