affiliation not provided to SSRN, affiliation not provided to SSRN, National University of Singapore (NUS) - Cancer Science Institute of Singapore, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, National University of Singapore (NUS) - Department of Pharmacy, affiliation not provided to SSRN, Hackensack Meridian Health - Center for Discovery and Innovation and National University of Singapore (NUS) - Department of Chemistry