affiliation not provided to SSRN, affiliation not provided to SSRN, Accenture, affiliation not provided to SSRN, CHU de Reims, affiliation not provided to SSRN, affiliation not provided to SSRN, Université de Paris Cité - INSERM, affiliation not provided to SSRN, affiliation not provided to SSRN, Pfizer, Inc. - Pfize France, affiliation not provided to SSRN, affiliation not provided to SSRN, Pfizer, Inc. - Pfize France, affiliation not provided to SSRN, affiliation not provided to SSRN, Accenture, affiliation not provided to SSRN, Université Paris Est Créteil - Sorbonne Université and affiliation not provided to SSRN

affiliation not provided to SSRN, affiliation not provided to SSRN, University of Rennes 1, CHU Rouen, affiliation not provided to SSRN, Université de Tours - Service de Cardiologie, Centre Hospitalier Pierre Bénite, Université Paris Est Créteil - Sorbonne Université, CHU de Reims, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University Hospital of Henri-Mondor, APHP - Reference Center for Major Sickle Cell Syndromes, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, CHU Caen, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Nantes - CHU Nantes, affiliation not provided to SSRN, University of Bordeaux - Hôpital Haut-Lévêque, CHU Montpellier, Université Clermont Auvergne - CHU Clermont-Ferrand, CHU Strasbourg, European Market Maintenance Assessment (EMMA), Université Paris-Dauphine, PSL Research University, affiliation not provided to SSRN and affiliation not provided to SSRN