affiliation not provided to SSRN, The University of Sydney - NHMRC Clinical Trials Centre, Shoalhaven District Memorial Hospital, Flinders University - Flinders Medical Centre, Border Medical Oncology, affiliation not provided to SSRN, affiliation not provided to SSRN, Austin Health, The University of Sydney - NHMRC Clinical Trials Centre, Monash University, affiliation not provided to SSRN, The University of Sydney - NHMRC Clinical Trials Centre, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Adelaide, Princess Alexandra Hospital, Monash Medical Centre, Princess Alexandra Hospital, The University of Sydney - NHMRC Clinical Trials Centre, The University of Sydney, affiliation not provided to SSRN and The University of Sydney - NHMRC Clinical Trials Centre