Ghent University, affiliation not provided to SSRN, Ghent University, Ghent University, Ghent University, Ghent University, affiliation not provided to SSRN, University of Illinois College of Medicine, University of Illinois College of Medicine, affiliation not provided to SSRN, Ghent University, Ghent University, Ghent University and University of Illinois at Chicago - Department of Biochemistry and Molecular Genetics