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James D. Brenton

University of Cambridge

SCHOLARLY PAPERS

2

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96

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Scholarly Papers (2)

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1.

Clinical Validation of a DNA Methylation Biomarker Associated with Overall Survival of Relapsed Ovarian Cancer Patients

Number of pages: 29 Posted: 17 Apr 2025
Muhammad Habiburrahman, Nahal Masrour, Naina Patel, Anna Pizkorz, Robert Brown, James D. Brenton, Iain McNeish and James Flanagan
Imperial College London - Department of Surgery and Cancer, Imperial College London, Imperial College London, University of Cambridge, Imperial College London, University of Cambridge, Imperial College London and Imperial College London - Department of Surgery and Cancer
Downloads 71 (867,774)

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Ovarian cancer, DNA methylation, epigenetic biomarker, platinum-based chemotherapy, survival

2.

Coordinated Protein Modules Define DNA Damage Responses to Carboplatin at Single Cell Resolution in Human Ovarian Carcinoma Models

Number of pages: 53 Posted: 22 Nov 2024
Jacob Seth Bedia, Ying-Wen Huang M.S, Antonio Delgado Gonzalez, Veronica D. Gonzalez, Ionut-Gabriel Funingana, Zainab Rahil, Alyssa Mike, Alexis Joy Lowbar, Maria Vias, Alan Ashworth, James D. Brenton, Wendy Fantl and Sneak Peek Administrator
Stanford University, Stanford University - Department of Obstetrics and Gynecology, Stanford University, Stanford University, University of Cambridge, Stanford University, Stanford University, Stanford University, University of Cambridge, University of California, San Francisco (UCSF), University of Cambridge, Stanford University - Department of Obstetrics and Gynecology and Independent
Downloads 25 (1,385,945)

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Tubo-ovarian high grade carcinoma, carboplatin resistance, mass cytometry/CyTOF, single cells, DNA damage response, UWB.298, (Cambridge Institute Ovarian (CIOV)1, CIOV2 and CIOV3), partition-based graph abstraction, Uniform Manifold Approximation and Projection/UMAP, non-negative matrix factorization