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Karsten Niefind

University of Cologne

Albertus-Magnus-Platz

Cologne, 50923

Germany

  • University of Cologne

SCHOLARLY PAPERS

2

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90

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0

Scholarly Papers (2)

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1.

Ior-160, a Ck2/Hdac Dual Inhibitor, Reduces Tumor Growth by Suppressing Akt Signaling in a Xenograft Triple-Negative Breast Cancer Model

Number of pages: 43 Posted: 11 Dec 2024
Ana Ramos, Irene Ortín, Laura Ochoa-Callejero, Christian Werner, Dirk Lindenblatt, Karsten Niefind, Alfredo Martínez and Beatriz de Pascual-Teresa
Universidad San Pablo CEU, Universidad San Pablo CEU, affiliation not provided to SSRN, University of Cologne, University of Cologne, University of Cologne, Center for Biomedical research of La Rioja (CIBIR) and Universidad San Pablo CEU
Downloads 53 (1,052,702)

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CK2, Breast Cancer, HDAC, MDA-MB-231, multitarget approach, xenograft, X-ray crystallography

2.

Novel Fluoro-brominated benzotriazoles as potential CK2 inhibitors. How does fluorination affect the properties of benzotriazoles?

Number of pages: 34 Posted: 11 Sep 2025
Sławomir Kasperowicz, Christian Werner, Małgorzata Podsiadła-Białoskórska, Ewa Szołajska, Agnieszka M. Maciejewska, Dirk Lindenblatt, Karsten Niefind, Jaroslaw Poznanski and Maria Winiewska-Szajewska
affiliation not provided to SSRN, University of Cologne, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Cologne, University of Cologne, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 37 (1,222,651)

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Casein kinase CK2, halogenated-1H-benzotriazole derivatives, fluorinated ligands, brominated ligands, catalytic subunit of casein kinase CK2 variant α/α', 4, 5, 6, 7-tetrabromo-1H-benzotriazole, 5, 6-dibromo-4, 7-difluoro-1H-benzotriazole, differential scanning fluorimetry, microscale thermophoresis