Southern Medical University - Department of Gastroenterology, Jinan University, Southern Medical University - Department of Gastroenterology, Southern Medical University - Guangdong Provincial Key Laboratory of Gastroenterology, Jinan University, Southern Medical University - Department of Gastroenterology, Medical College of Wisconsin, Southern Medical University - Department of Gastroenterology, National University of Singapore, Southern Medical University - Department of Gastroenterology, Southern Medical University - Guangdong Provincial Key Laboratory of Gastroenterology, Southern Medical University - Guangdong Provincial Key Laboratory of Gastroenterology, Prince of Wales Hospital and Southern Medical University - Department of Gastroenterology