Christopher B. Hurt

University of North Carolina (UNC) at Chapel Hill

SCHOLARLY PAPERS

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Scholarly Papers (1)

1.

Fixed Dosing Versus Weight-Based Dosing of HIV-1 Prophylactic Monoclonal Antibodies in Adults: A Pharmacokinetics Modeling Study

Number of pages: 23 Posted: 14 Jan 2025
Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Duke University - Departments of Surgery, Immunology, Molecular Genetics and Microbiology, Duke University - Departments of Surgery, Immunology, Molecular Genetics and Microbiology, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Family Health International, HPTN Leadership and Operations Center, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Government of the United States of America - National Institute of Allergy and Infectious Diseases, Fred Hutchinson Cancer Research Center, Harvard University - Brigham and Women’s Hospital, University of North Carolina (UNC) at Chapel Hill - School of Medicine, Government of the United States of America - National Institute of Allergy and Infectious Diseases, Kelly Government Solutions, Columbia University - Aaron Diamond AIDS Research Center, Columbia University - Irving Medical Center, Emory University - School of Medicine, University of North Carolina (UNC) at Chapel Hill, Harvard University - Beth Israel Deaconess Medical Center, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Emory University - Division of Infectious Diseases, University of KwaZulu-Natal - Centre for the AIDS Programme of Research in South Africa (CAPRISA), George Washington University - School of Medicine and Health Sciences, National Institutes of Health, Government of the United States of America - National Institute of Allergy and Infectious Diseases, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, University of North Carolina (UNC) at Chapel Hill - Department of Medicine, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, National Institutes of Health - Vaccine Research Center and Duke University - Departments of Surgery, Immunology, Molecular Genetics and Microbiology
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Abstract:

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HIV prevention, dosing strategy, exponent of body weight, two-compartment, population pharmacokinetics model, variability in exposure