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Marcelo A. Comini

Institut Pasteur de Montevideo

SCHOLARLY PAPERS

4

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190

TOTAL CITATIONS

0

Scholarly Papers (4)

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1.

Insights into the Chemico-Biological Interactions of Natural Sesquiterpene Lactones with the Thiol-Redox Metabolism of Pathogenic Trypanosomatids

Number of pages: 31 Posted: 27 Jan 2025
Florencia Sardi, Orlando Elso, Karen Perelmuter, Lucía Fiestas, Aldana M. Corlatti, Fernando Da Costa, Thomas J. Schmidt, Mariela Bollati-Fogolín, Valeria P. Sülsen and Marcelo A. Comini
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Universidade de Ribeirão Preto, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and Institut Pasteur de Montevideo
Downloads 62 (942,565)

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Trypanosomatids, terpenoids, thiol-redox homeostasis, glutathione, trypanothione, redox biosensor

2.

Unveiling Novel Pharmacophores and Hit Compounds for the Development of Anti-Virals to Treat Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2)

Number of pages: 20 Posted: 30 May 2025
Hugo Cerecetto Meyer, Belén Dávila, Martín Fló, Santiago Ruatta, Franca Lorenzelli, Andrea Medeiros, Jonathan Bastidas, Gonzalo Rodríguez, Elena Aguilera, María Fernanda García, Angel Heriberto Romero, Soonju Park, Jinyeong Heo, Honggun Lee, Yeonguk Jeon, Kyuho Paul Park, David Shum, Virginia López, Marcos Couto and Marcelo A. Comini
Universidad de la Republica, Universidad de la Republica, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Universidad de la Republica, Institut Pasteur Korea, Institut Pasteur Korea, Institut Pasteur Korea, Institut Pasteur Korea, Institut Pasteur Korea, Institut Pasteur Korea, affiliation not provided to SSRN, affiliation not provided to SSRN and Institut Pasteur de Montevideo
Downloads 53 (1,031,043)

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SARS-CoV-2, COVID-19, protease inhibitor, anti-viral activity, bis(arylidenyl)ketone derivatives, polyhedral boron derivatives

3.

Fenbendazole–Amino Acid Derivatives as Novel Anthelmintic Candidates: Synthesis, Activity Against Haemonchus Contortus, and in Silico Profiling. †

Number of pages: 50 Posted: 26 Aug 2025
Maximiliano Colobbio, Ramiro Teixeira, Gerardo Duarte, Mauricio Silvera, Jenny Carolina Saldaña, Magdalena Nieves, Andrea Medeiros, Marcelo A. Comini, Laura Domínguez, María Elisa Melian, Beatríz Munguía, Juan Ramos and Eduardo Manta
UdelaR - Instituto Polo Tecnológico de Pando, Universidad de la Republica - Universidad de la Republica Uruguay, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Institut Pasteur de Montevideo, Institut Pasteur de Montevideo, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN
Downloads 39 (1,196,171)

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Anthelmintics, Fenbendazole-amino acids derivatives, Haemonchus contortus, synthesis, Biological evaluation, In silico prediction, Physicochemical profiling

4.

Re(I) tricarbonyl multifunctional complexes: effects on Trypanosoma cruzi, Trypanosoma brucei, Leishmania infantum and tumor cells

Number of pages: 45 Posted: 05 Dec 2025
Gonzalo Scalese, Mariano Soba, Yiyi Zhang, Diego Benítez, Ignacio Machado, Leticia Pérez-Díaz, Kevin Cariou, Gilles Gasser, Marcelo A. Comini and Dinorah Gambino
affiliation not provided to SSRN, affiliation not provided to SSRN, Sorbonne University - PSL University, Institut Pasteur de Montevideo, affiliation not provided to SSRN, affiliation not provided to SSRN, Sorbonne University - PSL University, Sorbonne University - PSL University, Institut Pasteur de Montevideo and affiliation not provided to SSRN
Downloads 36 (1,249,711)

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Leishmania infantum, multifunctional metal compounds, Re(I) tricarbonyls, Trypanosoma brucei, Trypanosoma cruzi, tumor cells