Li Wang

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Discovery of Novel Nlrp3 Inhibitors Enabled by a High-Throughput Screen

Number of pages: 20 Posted: 28 Jan 2025
Stéphane Dorich, Anick Auger, Li Wang, Jason Burch, Charles Pellerin, Silas Chan, Marianne Raymond, Lingling Zhang, Amandine Chefson, Marie-Anne Germain, Silvana Jananji, Valérie Dumais, Samuel Gaudreault, Alexandre Caron, Émilie Dumas-Bérubé and Michael. A. Crackower
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Abstract:

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NLRP3 inhibitors, High-Throughput Screen (HTS), Scintillation Proximity Assay (SPA), brain penetrant, furan, pharmacodynamic model