Leeds Teaching Hospitals NHS Trust, Leeds Teaching Hospitals NHS Trust, Leeds Teaching Hospitals NHS Trust, Leeds Teaching Hospitals NHS Trust, Imperial College London - West Middlesex University Hospital, Autonomous University of Barcelona - Rheumatology Unit, University of Oxford - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Leeds - Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds - Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds - Leeds Institute of Rheumatic and Musculoskeletal Medicine and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and LIRMM, University of Leeds