affiliation not provided to SSRN, affiliation not provided to SSRN, University of Texas at Houston - Department of Melanoma Medical Oncology, Iwate Medical University, Shizuoka Cancer Center, Wakayama Medical University, University of Occupational and Environmental Health, Sapporo Medical University, Niigata Cancer Center Hospital, University of Tsukuba, affiliation not provided to SSRN, Shinshu University - Department of Dermatology, affiliation not provided to SSRN, Osaka International Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, Chiba University, Jichi Medical University, Kawasaki Medical School, affiliation not provided to SSRN, Kyoto Prefectural University of Medicine, affiliation not provided to SSRN, Nagoya City University, Saitama Medical University International Medical Center (SIMC) - Department of Skin Oncology/Dermatology, affiliation not provided to SSRN, Shiga University of Medical Science, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN