University of Southampton, University of Southampton, Queen's University Belfast, University of Southampton, Harvard University - T.H. Chan School of Public Health, Harvard University - T.H. Chan School of Public Health, University of Southampton - School of Cancer Sciences, University of Southampton - University Hospital Southampton NHS Foundation Trust, University of Southampton - School of Cancer Sciences, Harvard University - T.H. Chan School of Public Health, Harvard College, Harvard College, Harvard University - T.H. Chan School of Public Health, University of Southampton - School of Cancer Sciences, Harvard College, Harvard University - Harvard TH Chan School of Public Health and University of Southampton - Clinical Informatics Research Unit