affiliation not provided to SSRN, National and Kapodistrian University of Athens, Ospedale Santa Chiara - Azienda Ospedaliero Universitaria Pisana, affiliation not provided to SSRN, National and Kapodistrian University of Athens, Leiden University, Leiden University - Department of Vascular and Molecular Imaging, National and Kapodistrian University of Athens, University of Patras, University of Ioannina, National and Kapodistrian University of Athens, National and Kapodistrian University of Athens, affiliation not provided to SSRN, Imperial College London, Ospedale Santa Chiara - Azienda Ospedaliero Universitaria Pisana, affiliation not provided to SSRN, University of Ioannina, affiliation not provided to SSRN, Fondazione Toscana Gabriele Monasterio and affiliation not provided to SSRN