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Aya Mizuike

National Institute of Infectious Diseases

1-23-1 Toyama Shinjuku Yokyo

Japan

  • National Institute of Infectious Diseases

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Scholarly Papers (1)

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Optimised Lipid Nanoparticle-mRNA Vaccine Design: Minimising Pyrogenicity While Preserving Immunogenicity Through Immune Profiling

Number of pages: 63 Posted: 27 Feb 2025
Tomohiro Takano, Keigo Kumagai, Hitoshi Iuchi, Kazutaka Terahara, Aya Mizuike, Eita Sasaki, Yu Adachi, Ryutaro Kotaki, Shinichiro Ota, Mizuki Fujisawa, Tomoharu Mizukami, Kyoko Saito, Masanori Isogawa, Kohei Soga, Haruyo Nakajima-Adachi, Satoshi Hachimura, Kouji Kobiyama, Ken J. Ishii, Michiaki Hamada, Masayoshi Fukasawa, Masaharu Shinkai, Takayuki Matsumura and Yoshimasa Takahashi
National Institute of Infectious Diseases - Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Waseda University, National Institute of Infectious Diseases - Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, National Institute of Infectious Diseases, National Institute of Infectious Diseases - Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo Shinagawa Hospital, National Institute of Infectious Diseases, National Institute of Infectious Diseases, National Institute of Infectious Diseases, National Institute of Infectious Diseases, The University of Tokyo, The University of Tokyo, The University of Tokyo, The University of Tokyo, The University of Tokyo, Waseda University, National Institute of Infectious Diseases, Tokyo Shinagawa Hospital, National Institute of Infectious Diseases - Research Center for Drug and Vaccine Development and National Institute of Infectious Diseases - Research Center for Drug and Vaccine Development
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Abstract:

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mRNA vaccine, lipid nanoparticle, ionisable lipid, vaccine reactogenicity, interleukin-1