affiliation not provided to SSRN, Università di Bologna, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Catania, University of Pavia - Department of Public Health, Experimental and Forensic Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pavia - Department of Public Health, Experimental and Forensic Medicine, affiliation not provided to SSRN, Università degli Studi di Sassari, University of Pisa, Università degli Studi di Bari “Aldo Moro” (UNIBA), University of Catania, Universita degli Studi di Torino and Università degli studi di Modena e Reggio Emilia (UNIMORE) - Department of Biomedical, Metabolic and Neural Sciences