IRCCS Regina Elena National Cancer Institute, affiliation not provided to SSRN, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, affiliation not provided to SSRN, affiliation not provided to SSRN, Università Vita-Salute San Raffaele - IRCCS Ospedale San Raffaele, affiliation not provided to SSRN, affiliation not provided to SSRN, Istituto Superiore di Sanità, affiliation not provided to SSRN, PSL Research University - Institut Curie, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Medical University of Warsaw, European Institute of Oncology (IEO) IRCCS - Department of Experimental Oncology, Université Paris-Est Créteil - INSERM, affiliation not provided to SSRN, Mater Dei Hospital, affiliation not provided to SSRN, Medical University of Warsaw, Sciensano, affiliation not provided to SSRN, Universitätsklinikum Schleswig-Holstein, affiliation not provided to SSRN, PSL Research University - Institut Curie and Institut Curie - Department of Drug Development and Innovation (D3i)