Sichuan University, University of Nottingham, Ningbo - University of Nottingham Ningbo China, Sichuan University - West China Biomedical Big Data Center, University of Nottingham, Ningbo - University of Nottingham Ningbo China, Prince of Wales Hospital - The Chinese University of Hong Kong, affiliation not provided to SSRN, Dalian University of Technology, affiliation not provided to SSRN and University of Lincoln