Karolinska Institutet, Karolinska Institutet, Karolinska Institutet, Karolinska Institutet, Karolinska Institutet, Universitat de Barcelona, Humanitas University, University of Texas Health San Antonio, University of Texas Health San Antonio, University of California, Irvine - Department of Biological Chemistry, Mount Sinai Health System - Department of Genetics and Genomic Sciences, Karolinska Institutet, Karolinska Institutet, Universitat Pompeu Fabra (UPF), Karolinska Institutet, University of California, Irvine, Mount Sinai Health System - Department of Genetics and Genomic Sciences, University of California, Irvine - Center for Epigenetics and Metabolism, University of Texas Health San Antonio, Barcelona Institute of Science and Technology (BIST), Karolinska Institutet and Independent