Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Glasgow, University of Leeds, affiliation not provided to SSRN, Government of the United Kingdom, Department of Health, National Health Service (NHS), Mount Vernon Cancer Centre Northwood, University of Edinburgh - Edinburgh Cancer Centre, Bravis Hospital, University of Edinburgh, Catharina Hospital, Erasmus University Rotterdam (EUR), Radboud University Nijmegen - Radboud University Medical Center and University of Oxford