Memorial Sloan Kettering Cancer Center, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Mount Sinai Health System - Department of Medicine, Hematology and Medical Oncology, Mount Sinai Health System - Department of Medicine, Hematology and Medical Oncology, Mount Sinai Health System - Department of Medicine, Hematology and Medical Oncology, affiliation not provided to SSRN, Frimley Park Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Mount Sinai Health System - Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai - Department of Genetics and Genomic Sciences, affiliation not provided to SSRN and Mount Sinai Health System - Department of Medicine, Hematology and Medical Oncology