affiliation not provided to SSRN, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - Princess Margaret Cancer Centre, Princess Margaret Hospital, Princess Margaret Hospital, CancerCare Manitoba, affiliation not provided to SSRN, University of Calgary, University of Toronto - University Health Network, Dalhousie University, University of Western Ontario - London Health Sciences Centre, BC Cancer - Vancouver, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, CancerCare Manitoba, affiliation not provided to SSRN, University of Calgary, affiliation not provided to SSRN, Dalhousie University, University of Western Ontario - London Health Sciences Centre, BC Cancer Agency (BCCA), Princess Margaret Hospital, University of Toronto - Princess Margaret Cancer Centre, affiliation not provided to SSRN and affiliation not provided to SSRN