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Remo Guerrini

affiliation not provided to SSRN

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Identification of Pyrazolo-Piperidinone Derivatives Targeting Yap-Tead Interface 3 as Anticancer Agents Through Integrated Virtual Screening and Mass Spectrometry Proteomics

Number of pages: 84 Posted: 27 Apr 2025
Laura Scalvini, Lorenzo Tagliazucchi, Gain Marco Elisi, Dana Zappaterra, Maria Gaetana Moschella, Sebastian Fantini, Daniele Aiello, Remo Guerrini, Valentina Albanese, Salvatore Pacifico, Ludovica Lopresti, Giulia Malpezzi, Giulia Saporito, Stefania Ferrari, Lorena Losi, Cecilia Pozzi, Stefano Mangani, Gaetano Marverti, Alberto Venturelli, Glauco Ponterini, Domenico d'arca, Marco Mor and Maria Paola Costi
University of Parma, affiliation not provided to SSRN, University of Parma, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Siena, University of Siena, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Parma and affiliation not provided to SSRN
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PYRAZOLO-PIPERIDINONE derivatives as new leads for anti-dead 4 inhibition, TEAD4 function inhibition, anticancer activity against colorectal cancer, Mass Spectrometry whole cell proteomics, fluorescence anisotropy competítions assay