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Beate Presser

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Advancing Forced Degradation Studies: Design of Experiments for Enhanced Structure-Function Relationship Analysis in Biotherapeutics

Number of pages: 19 Posted: 09 May 2025
Klaus Kronsbein, Verena Nold, Armin Böhrer, Beate Presser, Tanja Gaissmaier, Katharina Schindowski, Boris Mizaikoff and Florian Krattenmacher
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Ulm University and affiliation not provided to SSRN
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Abstract:

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Forced degradation studies of antibodies, Design of Experiment to reduce the correlation structure in forced degradation studies, Partial-Least-Square-Regression for the elucidation of structure-function-relationships