University of Toronto, Princess Margaret Hospital, Princess Margaret Hospital, Princess Margaret Hospital, affiliation not provided to SSRN, Princess Margaret Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN, Princess Margaret Hospital, University of Toronto - University Health Network, University of Toronto - University Health Network, University of Toronto - University Health Network, affiliation not provided to SSRN, Princess Margaret Hospital, University of Toronto and Princess Margaret Hospital