affiliation not provided to SSRN, Juntendo University, affiliation not provided to SSRN, affiliation not provided to SSRN, Juntendo University, Juntendo University, affiliation not provided to SSRN, affiliation not provided to SSRN, Juntendo University, Juntendo University, Juntendo University, Juntendo University - Department of General Thoracic Surgery, Juntendo University, National Cancer Center Hospital - Department of Experimental Therapeutics and Juntendo University - Department of Respiratory Medicine