Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Osaka University - Genome Information Research Center, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, affiliation not provided to SSRN, Kanazawa University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University, Wakayama Medical University and Indiana University - Herman B Wells Center for Pediatric Research