affiliation not provided to SSRN, University of Cape Town (UCT), University of Bath, affiliation not provided to SSRN, University of California - Departments of Neurology, Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (UCLA), University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT), University of Cape Town (UCT) - Department of Pediatrics and Child Health, Vanderbilt University, Stellenbosch University, University of Cape Town (UCT) - Neuroscience Institute, University of Bath, University of Cape Town (UCT) - Department of Pediatrics and Child Health, University of Cape Town (UCT) - Neuroscience Institute and University of Cape Town (UCT) - Department of Pediatrics and Child Health