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Jie Chen

Shandong University of Technology

No: 88, Gongqingtuan west road

No. 88 Gongqingtuan Road

Zibo, 255012

China

  • Shandong University of Technology

SCHOLARLY PAPERS

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Scholarly Papers (1)

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Targeted Degradation of Programmed Death Ligand 1 with a Bispecific Aptamer-Based Lysosome-Targeting Chimera

Number of pages: 20 Posted: 26 Jul 2025
Yuyang Li, Yuyang Li, Jingrui Li, Renshuai Zhang, Ruixin Ge, Wei Pan, Jie Chen, Ning Ding, Min Liu and Songbo Xie
affiliation not provided to SSRN, affiliation not provided to SSRN, Shandong University of Technology, Shandong Normal University, affiliation not provided to SSRN, Shandong Normal University, Shandong University of Technology, Peking University - Key Laboratory of Carcinogenesis and Translational Research, Shandong Normal University and affiliation not provided to SSRN
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Abstract:

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cancer immunotherapy, programmed death ligand 1, targeted protein degradation, Aptamer, lysosome-targeting chimera