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Clóvis A.L. Pinto

A.C. Camargo Cancer Center

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Distinct CD4 T-Cell Subsets Predict Lung Cancer Immunotherapy Failure and Identify Patients for Dual Blockade

Number of pages: 53 Posted: 29 Jul 2025
Amanda B. Figueiredo, Guilherme F.B. Evangelista, Stephanie M.I. Ferreira, Larissa M. Kuil, Andrea T. Faccio, Karina H.M. Cardozo, Valdemir M. Carvalho, Clara M. Cavalcanti, Robert Balderas, Rodrigo P. Lopes, James Turner, Thaiany G. Souza-Silva, Juan C.S. Silva, Jonathan P. Avila, Helder Nakaya, Nayane A.L. Galdino, Ananda D. Lopes, Kátia L.P. Morais, Iasmim P. Santos, Helano Freitas, Jefferson L. Gross, Clóvis A.L. Pinto, Rubens Chojniak, Walderez Dutra, Vladmir Cordeiro de Lima and Kenneth Gollob
A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, Fleury Group - Fleury S.A., Fleury Group - Fleury S.A., Fleury Group - Fleury S.A., Memorial Sloan Kettering Cancer Center, BD Biosciences, BD Biosciences, University of Birmingham, Harvard University - Harvard Medical School, University of São Paulo (USP), Hospital Israelita Albert Einstein, University of São Paulo (USP) - Department of Clinical and Toxicological Analyses, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, A.C. Camargo Cancer Center, Federal University of Minas Gerais (UFMG) - Laboratório de Biologia das Interações Celulares, A.C. Camargo Cancer Center and A.C. Camargo Cancer Center
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Abstract:

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NSCLC, immune checkpoint inhibitors, therapy response, immunomodulation, biomarkers, immunotherapy, CD4 T cells