Zhejiang University - Centre for Global Health, Central South University - Department of Gastroenterology, Zhejiang University - Centre for Global Health, KU Leuven, Central South University - Department of Gastroenterology, Central South University - Department of Gastroenterology, Karolinska Institutet - Department of Medical Epidemiology and Biostatistics, Central South University - Department of Gastroenterology, Tel Aviv University - Sackler Faculty of Medicine, Zhejiang University - Department of Big Data in Health Science, Charité - Universitätsmedizin Berlin, Central South University - Department of Gastroenterology, Universidade do Porto and Central South University - Department of Gastroenterology