University of Salamanca, University of Salamanca, University of Salamanca, Carlos III National Institute of Health - Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), University of Salamanca, affiliation not provided to SSRN, SIGNATOPE GmbH, University of Salamanca, University of Salamanca - Experimental Hepatology and Drug Targeting (HEVEPHARM) Group and University of Salamanca