University of Southampton, University of Southampton - Medical Research Council Life Course Epidemiology Unit, University of Bristol, London School of Hygiene & Tropical Medicine, Biomedical Research and Training Institute, London School of Hygiene & Tropical Medicine, Government of the United Kingdom - Birmingham Women’s and Children’s NHS Foundation Trust, University of Bristol, University of Bristol, University of Bristol, University of Bristol, University of KwaZulu-Natal, London School of Hygiene & Tropical Medicine - Department of Clinical Research, University of Bristol - Musculoskeletal Research Unit and University of Southampton - Medical Research Council Life Course Epidemiology Unit