University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, affiliation not provided to SSRN, University of Colorado, Aurora - Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus and University of Colorado at Denver - Department of Bioengineering