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Zhixuan Ren

Fudan University - Huadong Hospital

Shanghai

China

  • Fudan University - Huadong Hospital

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Scholarly Papers (1)

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Exploratory Biomarker Analysis of PD-1/CTLA-4 Bispecific Antibody Therapy Response in PD-L1-Negative Advanced Non-Small Cell Lung Cancer: Genomic and Transcriptomic Profiling from the Phase II LungCadX Study

Number of pages: 35 Posted: 19 Aug 2025
Li Wang, Zhixuan Ren, Qi Wang, Li Liu, Shuai Lv, Minwei Bao, Tianqing Chu, Chuangzhou Rao, Jianing Chen, Tianlin Sun, Changbin Zhu, Jialin Qu and Chunxia Su
Tongji University, Fudan University - Huadong Hospital, Tongji University - Shanghai Pulmonary Hospital, Tongji University, University of South China, Tongji University, Shanghai Jiao Tong University (SJTU) - Shanghai Chest Hospital, University of Chinese Academy of Sciences, Tongji University, Amoy Diagnostics Co., Ltd., Amoy Diagnostics Co., Ltd., Qingdao University - Cancer Precision Medicine Center and Tongji University - Department of Medical Oncology
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Abstract:

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Non-small-cell lung cancer, PD-L1-negative, PD-1/CTLA-4 bispecific antibody, Patient-derived organoid, IFN-γ signaling pathway