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David Seher

affiliation not provided to SSRN

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Diflapolin derivatives with hydroxylated urea subunit shift dual sEH/FLAP inhibition towards direct and potent 5-LOX suppression

Number of pages: 54 Posted: 30 Aug 2025
Barbara Matuszczak, Thomas Hasenoehrl, David Seher, Lorenz Waltl, Michael Hoyer, Lucia Aulinger, Anna Lutz, Anita Siller, Harald Schennach and Andreas Koeberle
University of Innsbruck, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Innsbruck, University of Innsbruck, Tirol Kliniken GmbH, Tirol Kliniken GmbH and University of Graz
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Abstract:

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5-lipoxygenase activating protein (FLAP), soluble epoxide hydrolase (sEH), 5-lipoxygenase (5-LOX), diflapolin, inflammation