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Janelle Morton

Syneos Health

Raleigh, NC

United States

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Nanoparticle distribution in the central nervous system following intrathecal administration: a multi-modal analysis of lumbar versus cisterna magna routes

Number of pages: 43 Posted: 22 Sep 2025
Oluwatobi Helen Babayemi, Corinne Fotso, Sauradip Chaudhuri, Lindsey Sablatura, Cassandra Baker, Fred Christian Velasquez, Janelle Morton, Eva M. Sevick-Muraca and Rachael W. Sirianni
Rice University, affiliation not provided to SSRN, University of Massachusetts Worcester - UMass Chan Medical School, affiliation not provided to SSRN, McGovern Medical School at UTHealth, Rice University, Syneos Health, University of Texas at Houston, McGovern Medical School, Graduate School of Biological Sciences, Brown Foundation Institute of Molecular Medicine and Program in Neuroscience and University of Massachusetts Worcester - UMass Chan Medical School
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Abstract:

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Intrathecal, drug delivery, nanoparticle, central nervous system, cerebrospinal fluid, PET/CT, biodistribution