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Tom Jacobs

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Optimal preclinical models for human dose projection of SARS-CoV-2 small molecule direct-acting antivirals

Number of pages: 37 Posted: 19 Sep 2025
Francesca Toselli, Sofie Jacobs, Els Scheers, Tom Jacobs, Jordi Doijen, Joyce Hereijgers, Ken Keustermans, Liese Aerts, Marjolein van Heerden, Marnix Van Loock, Stephen W. Mason, Mario Monshouwer, Ellen Van Damme and Florence Herschke
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Abstract:

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SARS-CoV-2, direct-acting antiviral, human dose projection, preclinical model translatability, K18-hACE2 mouse, air-liquid interface.