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Shiyu Chen

Chinese Academy of Medical Sciences

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Performance of Digital Droplet PCR and Probe-capture Metagenomics in Pathogenic Diagnosis of Sepsis: A Multicenter Prospective Cohort Study

Number of pages: 78 Posted: 25 Sep 2025
Jingjia Zhang, Xu Mei, Juan Du, Xiangyi Liu, Bin Yang, Yan Geng, Xiaoli Zhong, YongJun Li, Jiang Xia, Huifang Liu, Bingxue Hu, Bin Yang, Dong Zhang, Haotian Gao, Wei Yu, Xiaobing Chu, Shiyu Chen, Qian Zhang and Qiwen Yang
Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Peking Union Medical College Hospital, Vision Medicals Co., Ltd, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Peking Union Medical College Hospital, Capital Medical University, Vision Medicals Co., Ltd, Xi'an Jiaotong University (XJTU), Yangzhou University - Subei People's Hospital of Jiangsu Province, Vision Medicals Co., Ltd, Pilot Gene Technologies Company Limited, Vision Medicals Co., Ltd, Vision Medicals Co., Ltd, Vision Medicals Co., Ltd, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Chinese Academy of Medical Sciences, Chinese Academy of Medical Sciences, Chinese Academy of Medical Sciences and Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Peking Union Medical College Hospital
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Abstract:

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Keywords: Sepsis, ddPCR, PC-mNGS, clinical relevant strain, 28-day survival