affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Aalborg University Hospital, affiliation not provided to SSRN, University Medical Center of the Johannes GutenbergUniversity Mainz - Center for Thrombosis and Hemostasis (CTH), Erasmus University Rotterdam (EUR) - Erasmus Medical Center (MC), affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Cardiff University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, King’s College London, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Hull - Hull York Medical School, Leiden University - Leiden University Medical Center (LUMC), affiliation not provided to SSRN, Leiden University - Department of Cardiology, affiliation not provided to SSRN, Leiden University - Leiden University Medical Center (LUMC), affiliation not provided to SSRN and affiliation not provided to SSRN