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Lixing Gan

Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine

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Lower Airway Dysbiosis Driven by Streptococcus mitis Promotes the Pathogenesis of Early Chronic Obstructive Pulmonary Disease

Number of pages: 60 Posted: 21 Oct 2025
Huaqi Guo, Manyi Pan, Chenchen Hou, Tianyu Zhou, Jiayuan Sun, Jin Bai, Yun Liu, XiaoJu Zhang, Junjie Yun, Lifen Yuan, Yu Xie, Yuntian Chen, Lixing Gan, Liying Zhang, Xiahui Ge, Dan Li, Weining Xiong and Lifeng Yan
Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory Medicine, Guangxi Medical University - Department of Respiratory and Critical Care Medicine, Guangzhou Medical University, Zhengzhou University, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine, Jilin University (JLU) - Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine and Shanghai Jiao Tong University (SJTU) - Department of Respiratory and Critical Care Medicine
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Abstract:

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early chronic obstructive pulmonary disease, lung microbiome, Streptococcus mitis, 16S, bacteriophage lysin